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Bora Acquires Pyros Pharmaceuticals to Bolster Upsher-Smith Rare Disease Product Portfolio

Upsher-Smith Expands Ongoing Partnership with Appco

Adds New Pipeline Product to its Portfolio

Maple Grove, MN – September 12, 2022 — Upsher-Smith Laboratories, LLC (Upsher-Smith) today announced that it has expanded its ongoing partnership with Appco Pharma LLC (Appco) with the addition of a near-term generic product opportunity to its portfolio. This collaboration is part of Upsher-Smith’s company-wide effort to grow the Company’s portfolio of products through strategic partnerships and product acquisitions.

“This agreement further expands an already solid working relationship between Upsher-Smith and Appco,” said Rich Fisher, President and COO, Upsher-Smith. “Appco has extensive skills and experience in the development of diverse dosage forms that span a wide range of therapeutic areas. Our long-standing partnership has yielded a number of commercial-stage products. We are pleased to add their development strengths to our core competencies and expand Upsher-Smith’s product portfolio to accelerate growth in the U.S.”

“We are pleased to add one more product to our partnership with Upsher-Smith,” said Srini Paruchuri, COO, Appco. “Appco highly values Upsher-Smith’s strength in sales and marketing which complements Appco’s development and manufacturing capabilities. We look forward to expanding and growing this partnership.’’

Upsher-Smith will open its world-class manufacturing facility in Maple Grove, MN later this year. The new, 270,000 square foot facility will have fully up-to-date serialization and packaging capabilities and has capacity and capabilities that can support contract manufacturing for third parties. To learn more, visit upshersmith02.wpengine.com.

About Upsher-Smith

Upsher-Smith Laboratories, LLC is a trusted U.S. pharmaceutical company that strives to improve the health and lives of patients through an unwavering commitment to high-quality products and sustainable growth. The company brings brands and generics to a wide array of customers, always backed by its attentive level of service, strong industry relationships, and dedication to consistent product supply. For more information, visit upshersmith02.wpengine.com.

About Appco

Established in 2012, Appco Pharma LLC is a New Jersey-based generic drug development and manufacturing company. It operates through U.S. FDA-approved manufacturing sites in Piscataway NJ. The Appco team has extensive skills and experience in the development of complex drugs including dosage forms like tablets, capsules, extended-release formulations, oral liquids and suspensions. For more information, visit www.appcopharma.com.

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